Perimeter Medical Imaging AI has built Claire™ — the first FDA-approved, AI-enabled imaging device designed to help surgeons assess cancer margins during breast-conserving surgery, in real time, before the patient leaves the operating table.
The Problem Roughly 20% of breast-conserving surgeries in the U.S. require a repeat operation — costing the healthcare system $677 million annually. The root cause is visibility: surgeons currently have no reliable intraoperative tool to detect microscopic cancer at the margins. Pathology results can take up to ten days, leaving patients waiting — and outcomes uncertain.
What Makes It Different Claire combines patented wide-field optical coherence tomography (OCT) with proprietary AI trained on over two million breast tissue images — a dataset only Perimeter can generate. It delivers 10x higher resolution than standard X-ray and ultrasound, visualizing microscopic features like blood vessels, glands, and ducts at the clinically relevant 2mm depth. In roughly 15 minutes, Claire scans excised tissue and highlights areas of concern, giving surgeons real-time prioritization support. It requires no infrastructure changes, works in any OR, and is portable enough for rural clinics and outpatient centers.
Crucially, every procedure makes Claire smarter — a self-reinforcing data flywheel no competitor can replicate.
Claire doesn’t replace pathology. It gives surgeons — and patients — the confidence to make the right call before closing.
